Defytime TAM Spray 20ml – defytime®

Defytime TAM Spray 20ml


Defytime TAM Spray with Aqueous Propolis helps to improve biological health, while preventing dry mouth, tooth decay and gum disease naturally.

  • Made in New Zealand from natural ingredients and free of sugar and preservatives.
  • Promotes production of saliva as well as providing active anti-bacterial properties against tooth decay, gingivitis and bad breath.
  • TAM targets telomeres in cells, leading to younger and healthier cells.
  • TAM is the most effective anti-aging compound available.

Defytime TAM Spray is independently certified as meeting USA food safety standards. Download Report


Telomere Analysis Case Study –
Comparison of telomere length using TAM Spray

The TAT (Telomere Analysis Technology) test is a biomarker that enables risk stratification and early prognosis of various diseases, including cancer. Analysis is done by blood test and measures telomere length in order to accurately evaluate the body’s biological age.

By using and taking supplements containing the telomerase inducing activator TAM, cell basic strength will be improved and telomere shortening will be reduced, i.e. rate of aging. Shown are 2 cases where the effects of TAM have been remarkable and biological age has been rejuvenated.

Learn more about Telomere Analysis Technology

Case A – Male aged 49 years:
First and second test results show estimated biological age reduced by 3.2 years

Case B – Female aged 67 years:
First and second test results show estimated biological age reduced by 4.6 years

Learn more about Telomere Analysis Technology


Water, Aqueous Propolis, Glycerin, Manuka Honey, Menthol, Sodium Bicarbonate, Flavour, Sucralose, Sodium Benzoate, Potassium Sorbate, Manuka Essential Oil, TAM CO314818.

Aqueous Propolis

Propolis is a natural compound made by bees. They collect resin from the buds of plants and mix it with enzymes to form a substance high in antioxidant and antibiotic properties. With its high levels of amino acids, minerals, vitamins and flavonoids and its anti-bacterial and anti-fungal properties, propolis is a powerful antiseptic agent and an initiator of the body’s own immune defences, inhibiting the spread of unwanted disease.

Manuka Honey

Manuka Honey is a monofloral honey produced in New Zealand from the nectar of Manuka flowers. Manuka Honey has many antibacterial properties as compared to normal honey. Manuka plants have historically been used by native Maori and early European settlers for medicinal purposes to treat colds, flu, and stomach aches. These special properties are unique to New Zealand Manuka Honey.

Manuka Essential Oil

Manuka Oil is derived from the leaves of the Manuka tree and is widely known for its excellent health benefits. Manuka Oil is antibacterial in nature and helps to inhibit bacterial growth. The anti-fungal and anti-inflammatory properties of Manuka Oil can fight skin irritation and infection. Manuka Oil is also known to be anti-histaminic and anti-allergenic making it a good natural alternative to calm bites and stings.

Telomerase Activating Molecule

Developed by Bill Andrews, Ph.D. of Sierra Sciences, LLC.) in 2014, TAM CO314818 is a state of the art Telomerase Activating Molecule (TAM) that counteracts and suppresses the fundamental cause of aging: telomere shortening.

By interfering with the action of telomerase inhibiting substances TAM CO314818 induces telomerase to function normally and to cause cell division to become more active leading to younger and healthier cells.

TAM is the most effective anti-aging compound available. All Defytime products feature the TAM logo to indicate they contain the TAM compound.

Telomeres are an essential part of human cells that affect how our cells age.

Cell division plays a critical role in normal growth, maintenance and repair of all human tissues.

Telomeres are repeated sequences of DNA at the ends of each chromosome and are key genetic elements involved with the regulation of cell division. Telomeres shorten every time a cell divides, and once telomeres reach a critically short length, the cell either dies by apoptosis or stops dividing and senesces.

Telomerase is a naturally occurring enzyme that maintains telomeres and prevents them from shortening during cell division.

Learn more about TAM and telomere research


For oral use. Apply 2-3 sprays directly on or under the tongue. Wait for 20 seconds before swallowing to absorb effectively. Apply twice a day (morning and evening). Shake before use.


Avoid use if allergic to bee stings or bee products.

Bill Andrews, Ph.D.
CEO of Sierra Sciences / R&D for Defytime

Our cutting edge research is led by Dr. Bill Andrews. Dr. Andrews has worked in the biotech industry for over 35 years, focusin